Autism–>Importance Of Gut Microbes: These are notes I have taken from sources about topics that interest me, and/or that have tremendously helped me along This Beautiful Journey called LIFE!!! … Many people ask me about all these things, and I decided to create a section where I post all this information. Hope you will also find it interesting and helpful… Please scroll down and click on the reference(s) for the complete information on this topic.
The Germs, Probiotics, And Mental Health
The Research
The Importance Of Gut Microbes
- may communicate with the brain and help us be social
- being social allows microbes to spread to others
Laboratory Studies: Germ-Free Mice
- no microbiome (microbes) in their intestines
- altered behavior and brain function
- unable to recognize other mice around them
- engage in “high-risk behavior”
- neurochemical changes in the brain
- genetic alterations in the animals’ brains
- studies in infancy:
- the absence or presence of gut microorganisms permanently alters gene expression
- absence of gut bacteria alters genes and signaling pathways involved in learning, memory, and motor control
- gut bacteria-closely tied to early brain development and subsequent behavior
- treatment=> expose germ-free mice to normal microorganisms
- the behavioral changes could be reversed if treated early in life
- once mice reached adulthood, treatment no longer effective
- when the intestines of germ-free mice were colonized with bacteria from other mice, they took on aspects of the donor’s personality
- germ-free mice also had leaky intestines and abnormal microbiomes (something common in children with autism)
- when treated with the microbe “bacteroides fragilis” → gut permeability was corrected and many behavioral symptoms went away
Psychobiotics: A New Treatment for Mental Health
What Some Scientists Believe
- beneficial microbes (psychobiotics) could one day be used to treat mental health problems in humans
- dietary treatments could one day be used as either adjunct or sole therapy for mood disorders
Other Research Findings
- women with high prolonged fevers during pregnancy→ more likely to have children with autism, leaky intestines and abnormal microbiomes
- findings in mice-studies→ potential probiotic therapy for gastrointestinal and behavioral symptoms in human neurodevelopmental disorders
References
- Mercola, J (2015, November 12). Mental Health May Depend on the Health of Your Gut Flora. Retrieved from: https://articles.mercola.com/sites/articles/archive/2015/11/12/mental-health-gut-flora.aspx
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